{
  "dataset": "CRAG open processed-coordinate validation cohort",
  "zenodo_record": "6914806",
  "doi": "10.5281/zenodo.6914806",
  "paper_doi": "10.1186/s13073-022-01141-8",
  "license": "CC BY 4.0 for the Zenodo record",
  "reference_build": "hg19 / GRCh37",
  "coordinate_contract": "liver records are zero-based half-open extended BED8 (name, MAPQ, strand, and two validated mate CIGAR columns); MAPQ is the smaller mate MAPQ according to the authors' README; the separately published BH01 example uses BED6",
  "author_preprocessing": "Adapters trimmed; BWA-MEM to human_g1k_v37; PCR duplicates removed by samblaster; proper unique autosomal pairs retained; fragments outside 50-1000 bp excluded for the paper analysis.",
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  "analysis_boundary": "Eight early-stage liver cancers and eight independent age/sex-matched noncancer controls are an exploratory matched engineering cohort. They cannot estimate MCED specificity or support a screening claim."
}
